RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-214
RNA ID
MI0000698
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; Masson's trichrome staining
Target
MMP-1;TIMP-1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
27357906
Title
MicroRNA-214 Exerts a Cardio-Protective Effect by Inhibition of Fibrosis
Year
2016
Function
miR-214 exerts cardio-protective effects by inhibition of fibrosis and the inhibitory effect involves TGF-beta1 suppression and MMP-1/TIMP-1 regulation.